Bone marker response in chronic diffuse sclerosing osteomyelitis treated with intravenous ibandronate

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196. Bone Marker Response in Chronic Diffuse Sclerosing Osteomyelitis Treated with Ibandronate

Background: CDSO is a condition affecting predominantly the mandible and long bones of young females, characterised by episodes of intractable pain on a background of chronic discomfort. The aetiology is unknown, but the bone sclerosis is associated with abnormal osteoblast and osteoclast function. Methods: We report 3 cases in which symptoms and biochemical markers responded to treatment with ...

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[Chronic sclerosing osteomyelitis].

In 1893 Ganr#{233} described a sclerosing form of osteomyelitis that caused distension and thickening of bone, but no suppuration, sequestration or fistula formation. Hardmeier, Uehlingen and Muggli (1974) introduced the term primary chronic sclenosing osteomyelitis to differentiate the clinical presentation of chronic osteomyelitis from the clinical description given by Garr#{233} ; they also ...

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[Garre's chronic sclerosing osteomyelitis with sacral involvement in a child].

We report the case of a 6 year old patient who started with abdominal pain and left sciatica, which did not improve after applying symptomatic treatment. A complete analytical and imaging study was performed, which showed a lesion in left S1 corresponding to Garrè's chronic diffuse sclerosing osteomyelitis. The diagnosis was confirmed by biopsy of the lesion. Treatment was established with cort...

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Bone scintigraphy in diagnosing chronic recurrent multifocal osteomyelitis

A 10-year-old boy was referred to us for evaluation of FUO accompanied with bone pain in both calves. Three hours after intravenous injection of 13 mCi of 99mTc-MDP, whole body scan in multiple spot views was performed. The scan showed symmetrical areas of diffusely increased tracer uptake in multiple long bones. Histopathologic evaluation confirmed osteosclrosis and fibrotic changes...

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Chronic Sclerosing Osteomyelitis of the Mandible Treated with Hemimandibulectomy and Fibular Free Flap Reconstruction.

Primary chronic osteomyelitis of the mandible is a rare condition that presents with a long-standing chronic facial swelling over the mandible, pain with mastication, and trismus. With no clinically appreciated acute phase, the aetiology often remains unknown. Many patients achieve adequate symptom control with broad-spectrum antibiotics, hyperbaric oxygen therapy and surgical debridement, or d...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2005

ISSN: 0003-4967

DOI: 10.1136/ard.2005.047217